Acharyulu, M. L. N. and Mohana Rao, P. V. S. R. and Koti, I. Siva Rama (2021) Recent Development and Validation of Sodium Nitroprusside in Visible Spectrophotometric Determination of Triprolidine Hydrochloride. In: Challenges and Advances in Chemical Science Vol. 2. B P International, pp. 1-8. ISBN Dr. Harekrushna Sutar Challenges and Advances in Chemical Science Vol. 2 07 26 2021 07 26 2021 9789391312077 Book Publisher International (a part of SCIENCEDOMAIN International) 10.9734/bpi/cacs/v2 https://stm.bookpi.org/CACS-V2/issue/view/264
Full text not available from this repository.Abstract
Objective: A simple and sensitive extractive visible spectrophotometric method is developed for the assay of Triprolidine Hydrochloride using Sodium nitroprusside.
Methods: Based on color development with amino groups, presence, which is basic, may be due to the formation of inner complex replacing H2O by the tertiary amino group present in the drug.
Results: The colored products exhibit absorption
max at 447 nm. Regression analysis of Beer–Lambert plots showed good correlation in the concentration ranges (40–240)
g/ml and correlation coefficients are 0.994. The Sandell’s sensitivities 2.6373×10-2 (1 mole cm-1) and molar absorptivity value are 1.1938×104 (g cm-2). Recovery studies are found to be 99.708–99.786.
Conclusion: The method can be applied successfully for the estimation of the drug in the presence of other ingredients that are usually present in formulations. The proposed method reports a new way for the determination of Triprolidine Hydrochloride (TPH) in pharmaceuticals.
| Item Type: | Book Section |
|---|---|
| Subjects: | Article Paper Librarian > Chemical Science |
| Depositing User: | Unnamed user with email support@article.paperlibrarian.com |
| Date Deposited: | 27 Oct 2023 04:56 |
| Last Modified: | 27 Oct 2023 04:56 |
| URI: | http://editor.journal7sub.com/id/eprint/1961 |
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