Quercetin Supplementation Reduces Maternal Hyperglycemia in a Type 2 Diabetes Mellitus Mouse Model

Gutierrez, J. Claudio and Prater, M. Renee and Holladay, Steven D. (2013) Quercetin Supplementation Reduces Maternal Hyperglycemia in a Type 2 Diabetes Mellitus Mouse Model. Annual Research & Review in Biology, 4 (1). pp. 306-311. ISSN 2347565X

[thumbnail of 26625-Article Text-49973-1-10-20190109.pdf]

Text
26625-Article Text-49973-1-10-20190109.pdf - Published Version
Download (305kB)

Official URL: https://doi.org/10.9734/ARRB/2014/5431

Abstract

Aims: Pregnancy may be complicated by diabetes mellitus. The use of natural antioxidants may alleviate the increased glucose levels in the diabetic pregnancy.
Methodology: The combination of high Fat Diet (HFD) and streptozocin (STZ) was used pre-breeding in CD1 female mice to generate maternal hyperglycemia. A subgroup of the females received quercentin (Q) supplementation in their HFD.
Results: Hyperglycemic females supplemented with Q displayed significantly decreased blood glucose levels at gestation days 10 and 17.
Conclusion: These results suggest quercetin could have utility as a supplement for diabetic women during pregnancy, and could represent a protection for the offspring of diabetic mothers.

Item Type:	Article
Subjects:	Article Paper Librarian > Biological Science
Depositing User:	Unnamed user with email support@article.paperlibrarian.com
Date Deposited:	02 Oct 2023 12:43
Last Modified:	02 Oct 2023 12:43
URI:	http://editor.journal7sub.com/id/eprint/1617

Actions (login required)

: View Item